Research focuses on the physico-chemical properties (e.g., size, shape, surface charge, and functionalization, stability and reactivity) of manufactured and engineered nanomaterials of commercial importance (e.g., gold, silver, ceria, titania, and cellulose). Activities encompass the development and validation of advanced methods and novel instrumentation. Emphasis is on addressing pre-competitive research that supports industry needs for advanced nanomaterials development, quality control, and regulatory requirements.