Label-free Optical Medical Imaging

Exogenous labeling of biomolecules often introduces artifacts in the measurement of structures and functions of the molecules. Furthermore, specific molecular labeling sometimes is not practical in many clinical imaging and diagnostics. This research focuses on developing and applying label-free optical imaging technologies to visualize structures and molecular compositions of organelles in cells and to map heterogeneities in tissues to enable quantitative biophysical studies of cells and optical biopsies of tissues. Ongoing rese...