Funder: National Institutes of Health
Due Dates: June 2, 2025 (New, Renewal, Resubmission, Revision) | February 2, 2026 | October 1, 2026 | June 2, 2027
Funding Amounts: Up to $350,000 direct costs/year for each phase; max 5 years total (R61: 1–2 years, R33: remainder); modular or detailed budget allowed.
Summary: Supports milestone-driven mechanistic research to identify person-specific features affecting probiotic responses, aiming to accelerate precision probiotic interventions and improve clinical outcomes.
Key Information: Applications must include clear milestones and R61-to-R33 transition criteria; efficacy/effectiveness trials are not supported; companion R33-only NOFO available for projects not needing the R61 phase.