Atom | HEAL Initiative: Research to Increase Implementation of Substance Use Preventive Services (R61/R33 Clinical Trial Optional)

Due Dates: June 17, 2025 | January 16, 2026

Funding Amounts: No set limit; recommended maximum $300,000 direct costs/year (R61 phase, up to 2 years) and $750,000 direct costs/year (R33 phase, up to 4–5 years); total project period up to 6 years.

Summary: Supports research to develop and test innovative strategies for implementing and sustaining substance use preventive services, with a focus on opioid misuse prevention infrastructure.

Key Information: Phased R61/R33 mechanism; pilot data not required at submission; meaningful engagement of end users is required; clinical trial optional.

HEAL Initiative: Research to Increase Implementation of Substance Use Preventive Services (R61/R33 Clinical Trial Optional)

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