Atom | Mechanistic Research on Neuromodulation for Substance Use Disorders Treatment (R01 Basic Experimental Studies with Humans Required)

Funder: National Institutes of Health

Due Dates: August 14, 2025 (Renewal/Resubmission/Revision) | January 16, 2026 (New & Renewal/Resubmission/Revision) | August 14, 2026 (Renewal/Resubmission/Revision)

Funding Amounts: ~$1.5M/year for up to 6 awards across related NOFOs; no budget cap, but budgets must reflect actual project needs; max project period: 5 years.

Summary: Supports basic experimental studies in humans to identify and validate novel non-invasive brain stimulation targets and SUD-relevant neurobiological, cognitive, and behavioral responses that precede clinical outcomes.

Key Information: Applications must propose basic experimental studies with humans (BESH) that meet both the NIH clinical trial and basic research definitions; annual milestones are required.

Mechanistic Research on Neuromodulation for Substance Use Disorders Treatment (R01 Basic Experimental Studies with Humans Required)

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