2027 MIND Prize supports early-to-mid-career investigators pursuing bold, hypothesis-driven neuroscience research to advance understanding, prevention, and treatment of neurodegenerative diseases.
Funder: Pershing Square Philanthropies
Due Dates (Anticipated): September 2027 (Letter of Intent)
Funding Amounts: $750,000 over three years ($250,000 per year)
Summary: Supports bold, hypothesis-driven neuroscience research to advance understanding, prediction, prevention, and treatment of neurodegenerative diseases.
Key Information: Applicants must have one to eight years of independent research experience at a U.S. nonprofit research institution.
The MIND Prize (Maximizing Innovation in Neuroscience Discovery) is The Pershing Square Foundation’s brain initiative supporting early-to-mid-career investigators pursuing transformative neuroscience research. It seeks scientifically sound, high-risk, high-reward projects that challenge conventional paradigms and may be too speculative for traditional funding. Its priorities include fundamental understanding of brain biology and cognition, with particular attention to Alzheimer’s disease, dementias, and other neurodegenerative and neurocognitive disorders.
The prize encourages interdisciplinary work and collaboration across departments and institutions. Research may encompass neurobiology, brain imaging and mapping, machine learning, drug delivery, and synthetic biology, including novel tools and approaches with therapeutic potential. Technology development must test a clearly defined biological hypothesis rather than serve as a standalone platform. Investigators with or without core neuroscience backgrounds are encouraged to apply.