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    Microfluidics and Lab-on-a-Chip Technologies for Controlled Molecular Self-Assembly, Analytical Biochemistry, and Multiplexed Measurements

    This grant explores using microfluidics to control molecular self-assembly for biochemical analysis, drug development, toxin detection, and cell studies.

    This grant is no longer accepting proposals

    NRC Research Associateship Programs has archived this opportunity.

    Funder: NRC Research Associateship Programs

    Due Dates: February 1, 2025 | May 1, 2025 | August 1, 2025 | November 1, 2025

    Funding Amounts: Stipend approximately $82,764 per year with $3,000 travel allowance; typical appointment duration 2 years.

    Summary: Supports postdoctoral research using microfluidics and lab-on-a-chip technologies to study controlled molecular self-assembly, biochemical analysis, and multiplexed measurements.

    Key Information: Open to U.S. citizens with a doctoral degree earned within the last 5 years; applications require contacting a Research Adviser prior to applying; NIST participates in February and August review cycles only.

    Description

    This fellowship opportunity is offered through the NRC Research Associateship Programs at the National Institute of Standards and Technology (NIST), specifically within the Material Measurement Laboratory, Biomolecular Measurement Division in Gaithersburg, MD.

    The research focus is on leveraging microfluidic systems and lab-on-a-chip technologies to investigate and control molecular self-assembly processes. These systems exploit the unique physics of fluid flow, mass transfer, heat transfer, and reaction kinetics at micro- and nanoscale dimensions. The goal is to study supramolecular assemblies such as liposomes, lipid tubules, protein-based therapeutics, and other biomimetic particles.

    Recent work includes using microfluidics to understand protein therapeutic aggregation, a critical issue in biopharmaceutical development. The program also explores how nano- and microscale self-assembled biomimetic particles can facilitate and control molecular recognition, toxin and biowarfare agent detection, DNA analysis, nanofabrication, single-cell assays, and cell culture within microfluidic environments.

    The research group is highly interdisciplinary, welcoming applicants from diverse fields including chemical engineering, biomedical engineering, material science, electrical engineering, chemistry, mechanical engineering, physics, and biology.

    Keywords

    DNA, Drug delivery, Light scattering, Liposomes, Microfluidics, Nanoparticles, Nanotechnology, Reactions, Self-assembly, Separations, Protein therapeutics

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