This grant supports the development of miniaturized and automated tissue chip systems for drug development and biomedical research, with a focus on higher throughput measurements, rapid data analysis, and reduced manual handling. Small business participants will collaborate with NIH staff to achieve project goals and commercialize the system.
National Institutes of Health has archived this opportunity.
Funder: National Institutes of Health (NIH)
Due Dates: November 17, 2025
Funding Amounts: Cooperative agreement; funding amounts vary; see RFA for specifics.
Summary: Supports small businesses to develop automated, miniaturized tissue chip systems for high-throughput biomedical research and drug development.
Key Information: Only U.S. small businesses are eligible; foreign entities are not allowed.
This opportunity provides support for small businesses to advance the miniaturization and automation of tissue chip systems (MATChS) using the Small Business Technology Transfer (STTR) cooperative agreement mechanism. The goal is to foster the development of tools and turnkey technologies that enable higher throughput, automated measurements with online sensing, rapid data acquisition, and analysis—reducing manual handling in tissue chip platforms. These innovations are intended to enhance the availability and utility of automated tissue chip systems in drug development and as versatile research tools in biomedical laboratories. Funded projects are expected to work closely with NIH staff, establish project milestones, and demonstrate clear pathways toward commercialization.