The PRMRP Discovery Award is intended to support innovative, untested, non-incremental, high-risk/potentially high-reward research that will provide new insights, paradigms, technologies, or applications. The proposed project may be exploratory, hypothesis-driven, or hypothesis-generating research but must be novel and must be based on a strong scientific rationale and a well-developed study design and plan of analysis. Studies supported by this award are expected to lay the groundwork for future avenues of scientific investigati...