Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Not Allowed)
NIH Small Business Transition Grant supports new entrepreneurs in developing business skills while conducting research to advance healthcare technologies.
This grant is no longer accepting proposals
National Institutes of Health has archived this opportunity.
Funder: National Institutes of Health (NIH)
Due Dates: November 17, 2025 (Full application)
Funding Amounts: Award size varies by phase and project; budget must be reasonable for project scope. No cost-sharing required.
Summary: Supports the entrepreneurial career transition of researchers new to small business by funding both research/development and structured entrepreneurial training within U.S. small businesses.
Key Information: Clinical trials are not allowed; small business concerns (SBCs) must be the applicant.
Description
This opportunity from the National Institutes of Health (NIH) is designed to facilitate the career transition of investigators who are new to entrepreneurship and interested in working within small businesses. The program supports small business concerns (SBCs) in employing and developing researchers as entrepreneurial Program Directors/Principal Investigators (PDs/PIs), combining research and development activities with structured entrepreneurial training, mentoring, and career development. The primary goal is to help scientists and professionals with strong technical backgrounds but limited entrepreneurial experience to acquire the skills necessary to lead independent research projects and commercialize health-related technologies and products aligned with the NIH mission.
