Funder: National Institutes of Health

Due Dates: August 6, 2025 (Letter of Intent) | September 5, 2025 (Application) | December 6, 2025 (LOI) | January 5, 2026 (App) | March 6, 2026 (LOI) | April 5, 2026 (App) | August 6, 2026 (LOI) | September 5, 2026 (App) | December 6, 2026 (LOI) | January 5, 2027 (App) | March 6, 2027 (LOI) | April 5, 2027 (App)

Funding Amounts: Phase I: up to $306,872 (6 months) | Phase II: up to $2,045,816 (2 years); higher budgets possible for select topics with prior approval

Summary: Supports early-career researchers transitioning to entrepreneurship by funding both their business training and R&D in small businesses aligned with NIH’s health mission.

Key Information: Clinical trials are not allowed; strong emphasis on mentorship and entrepreneurial career development; only U.S. small businesses are eligible to apply.