Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Not Allowed)
This grant supports new entrepreneurs in small businesses by aiding career development, research, and entrepreneurial training for researchers-turned-entrepreneurs.
This grant is no longer accepting proposals
National Institutes of Health has archived this opportunity.
Funder: National Institutes of Health (NIH)
Due Dates: November 17, 2025 (full proposal)
Funding Amounts: Typical Phase I: up to $275,766 (6-12 months) | Typical Phase II: up to $1,838,436 (up to 2 years); actual amounts may vary by institute and project scope.
Summary: Supports small businesses in hiring and developing early-career researchers as entrepreneurial PIs, providing both research funding and structured entrepreneurial training to foster biomedical innovation.
Key Information: Only U.S.-based small businesses are eligible; foreign entities are not eligible to apply.
Description
This opportunity from the NIH is designed to help small business concerns (SBCs) recruit and develop researchers who are new to entrepreneurship. The program simultaneously supports the entrepreneurial development of the Program Director/Principal Investigator (PD/PI) and the research and development (R&D) activities under their direction. The goal is to enable talented scientists and professionals with strong research or technology backgrounds, but limited entrepreneurial experience, to gain the skills needed to lead innovative projects in the small business sector. The focus is on advancing technologies and products that align with NIH’s mission to improve health.
