BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)
Funding for research on advanced behavior measurement tools and computational models, emphasizing multidimensional data integration at the organismal level, excluding clinical trials under the BRAIN Initiative.
This grant is no longer accepting proposals
National Institutes of Health has archived this opportunity.
Funder: National Institutes of Health
Due Dates: September 9, 2025 (Letter of Intent) | October 9, 2025 (Full Application) | September 9, 2026 (Letter of Intent) | October 9, 2026 (Full Application)
Funding Amounts: Estimated $8M/year across this and companion NOFO; up to 10 U01 awards/year; budgets not limited, max project period 5 years.
Summary: Supports transdisciplinary research to develop and integrate advanced tools and computational models for high-resolution, multidimensional measurement of behavior at the organismal level, excluding clinical trials.
Key Information: Applications must use non-human animal models; human research is not allowed under this NOFO; a Plan for Enhancing Diverse Perspectives (PEDP) is required.
Description
This opportunity, part of the NIH BRAIN Initiative, seeks to fund transformative, integrative research that advances the measurement and modeling of behavior at the organismal level in non-human animal models. The focus is on developing and validating minimally invasive, high-resolution, multidimensional behavioral measurement tools, synchronously capturing environmental data, and creating computational models that integrate behavioral, neural, and environmental data across multiple timescales. Projects must be designed to enable integration of synchronously recorded neural data and/or inform models of neurobehavioral function.
Clinical trials and research involving human subjects or human data as a significant component are not allowed under this NOFO. Applicants interested in mechanistic research in humans should apply to the companion NOFO RFA-DA-24-040.
A Plan for Enhancing Diverse Perspectives (PEDP) is required and will be evaluated during peer review. Applications lacking a PEDP will be withdrawn.
