Funder: National Institutes of Health

Due Dates: June 12, 2025 (New) | July 12, 2025 (Renewal/Resubmission/Revision) | October 12, 2025 (New) | November 12, 2025 (Renewal/Resubmission/Revision) | February 12, 2026 (New) | March 12, 2026 (Renewal/Resubmission/Revision) | June 12, 2026 (New) | July 12, 2026 (Renewal/Resubmission/Revision) | October 12, 2026 (New) | November 12, 2026 (Renewal/Resubmission/Revision) | February 12, 2027 (New) | March 12, 2027 (Renewal/Resubmission/Revision) | June 12, 2027 (New) | July 12, 2027 (Renewal/Resubmission/Revision)

Funding Amounts: Up to $125,000/year salary + $50,000/year research development costs; project period up to 5 years; indirect costs at 8% MTDC.

Summary: Supports mentored career development for clinician-scientists to establish independent research programs in pain management, focusing on basic experimental studies with humans (BESH) under the NIH HEAL Initiative.

Key Information: Applicants must propose independent BESH clinical trials; attendance at the annual PURPOSE Meeting is required; strong pre-submission consultation with NIH staff is encouraged.