Funder: National Institutes of Health

Due Dates: May 17, 2025 (LOI for June 16, 2025) | June 16, 2025 (New) | July 16, 2025 (Renewal/Resubmission/Revision) | Sept 16, 2025 (LOI for Oct 16, 2025) | Oct 16, 2025 (New) | Nov 16, 2025 (Renewal/Resubmission/Revision) | Additional cycles through Nov 16, 2027

Funding Amounts: Up to $100,000 in direct costs for a 1-year project; non-renewable; no cost sharing required.

Summary: Supports pilot projects generating preliminary data or tools to study eligible understudied proteins associated with rare diseases; clinical trials are not allowed.

Key Information: Project must focus on one or more eligible proteins (see list); must address a rare disease (≤200,000 U.S. prevalence); clinical trials are not permitted.