Support research in implementing effective health interventions, especially in underrepresented communities, while also exploring the cessation of ineffective practices and improving research methods.
Funder: National Institutes of Health
Due Dates: June 5, 2025 (New) | July 5, 2025 (Renewal/Resubmission/Revision) | September 7, 2025 (AIDS) | October 5, 2025 (New) | November 5, 2025 (Renewal/Resubmission/Revision) | January 7, 2026 (AIDS) | Standard NIH R01 due dates through January 7, 2028
Funding Amounts: No budget limit; project period up to 5 years; budgets must reflect actual needs.
Summary: Supports research to identify, develop, and test strategies for disseminating, implementing, and sustaining evidence-based health interventions, including de-implementation of ineffective practices.
Key Information: Clinical trials are optional; foreign and domestic organizations are eligible; all applications must align with the mission of a participating NIH Institute or Center.
This opportunity supports research projects that advance the science of dissemination and implementation (D&I) in health. The focus is on identifying, developing, and testing strategies to overcome barriers to the adoption, adaptation, integration, sustainability, scale-up, and spread of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Projects may also address the de-implementation of ineffective, unproven, low-value, or harmful practices.
The program encourages studies that:
Applications must be within the mission of at least one participating NIH Institute or Center. Multidisciplinary and stakeholder-engaged approaches are strongly encouraged.