Funder: National Institutes of Health

Due Dates: June 5, 2025 (New) | July 5, 2025 (Renewal/Resubmission/Revision) | September 7, 2025 (AIDS) | October 5, 2025 (New) | November 5, 2025 (Renewal/Resubmission/Revision) | January 7, 2026 (AIDS)

Funding Amounts: No budget cap; budgets must reflect actual project needs. Maximum project period: 5 years.

Summary: Supports development of advanced human cell-derived microphysiological systems (MPS) to model complex nervous system architecture and function; clinical trials are not allowed.

Key Information: Applications requesting ≥$500,000 direct costs in any year require prior NIH contact at least 6 weeks before submission.