Funder: National Institutes of Health

Due Dates: June 5, 2025 (New) | July 5, 2025 (Renewal/Resubmission/Revision) | October 5, 2025 (New) | November 5, 2025 (Renewal/Resubmission/Revision) | February 5, 2026 (New) | March 5, 2026 (Renewal/Resubmission/Revision) | June 5, 2026 (New) | July 5, 2026 (Renewal/Resubmission/Revision)

Funding Amounts: No budget cap; budgets must reflect actual needs. Project period up to 5 years. Typical R01 awards range from $200,000–$500,000/year in direct costs.

Summary: Supports research on the cellular and molecular biology of high-confidence risk factors in complex brain disorders, focusing on neural function substrates using experimental paradigms.

Key Information: Clinical trials are not allowed; companion R21 available for early-stage exploratory projects.