Funder: National Institutes of Health

Due Dates: June 16, 2025 (New) | July 16, 2025 (Renewal/Resubmission/Revision) | October 16, 2025 (New) | November 16, 2025 (Renewal/Resubmission/Revision) | February 16, 2026 (New) | March 16, 2026 (Renewal/Resubmission/Revision) | June 16, 2026 (New) | July 16, 2026 (Renewal/Resubmission/Revision)

Funding Amounts: Up to $275,000 direct costs over 2 years; no more than $200,000 in any single year; project period max 2 years.

Summary: Supports exploratory research on mechanisms linking social disconnection (isolation, loneliness) and suicide risk in late life, including intervention target identification and prevention strategies.

Key Information: R21 mechanism; clinical trial optional but must be mechanistic; foreign and domestic applicants eligible.