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    Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trial Not Allowed)

    The INCLUDE Project supports innovative research developing animal models & biological materials for Down syndrome research, aiming to enhance data access & quality in DS studies using advanced technologies.

    This grant is no longer accepting proposals

    National Institutes of Health has archived this opportunity.

    Funder: National Institutes of Health

    Due Dates: February 16, 2025 (New) | March 16, 2025 (Renewal/Resubmission/Revision) | June 16, 2025 (New) | July 16, 2025 (Renewal/Resubmission/Revision) | October 16, 2025 (New) | November 16, 2025 (Renewal/Resubmission/Revision)

    Funding Amounts: Up to $200,000 direct costs per year; max $275,000 direct costs over 2 years; project period up to 2 years.

    Summary: Supports exploratory research to develop, characterize, or improve animal models and related biological materials for Down syndrome research, enhancing access and rigor in DS studies.

    Key Information: Clinical trials are not allowed; foreign organizations are not eligible to apply.


    Description

    This NIH opportunity, part of the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project, funds exploratory and innovative research to develop, characterize, or improve animal models and related biological materials for Down syndrome (DS) research. The goal is to advance preclinical and basic science studies relevant to DS and to improve access to information and resources derived from animal models. Projects may focus on new or improved animal models, genetic resources, single-cell or subcellular atlases, advanced informatics (including AI/ML), and integration of multiple models or platforms to enhance rigor and reproducibility in DS research.


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