Funder: National Institutes of Health

Due Dates: June 16, 2025 (New) | July 16, 2025 (Renewal/Resubmission/Revision) | October 16, 2025 (New) | November 16, 2025 (Renewal/Resubmission/Revision) | February 16, 2026 (New) | March 16, 2026 (Renewal/Resubmission/Revision) | June 16, 2026 (New) | July 16, 2026 (Renewal/Resubmission/Revision)

Funding Amounts: Up to $100,000 direct costs for a 1-year project; non-renewable R03 mechanism.

Summary: Supports pilot projects to identify new druggable pain targets among a defined list of understudied proteins, generating preliminary data/tools to advance pain and opioid addiction research.

Key Information: Applications must focus on eligible proteins listed in the NOFO; clinical trials are not allowed.