Atom | Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)

Funder: National Institutes of Health (NIH)

Due Dates: June 11, 2025 | October 10, 2025 | January 12, 2026

Funding Amounts: No budget cap, but requests must reflect project needs; up to 5 years total (1 year R61, 4 years R33)

Summary: Supports investigator-initiated, single-site clinical trials (R61/R33) relevant to NHLBI’s mission, using a milestone-driven, two-phase mechanism.

Key Information: R33 phase funding contingent on meeting R61 milestones; staff consultation required for direct costs ≥$500,000 in any year.

Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)

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