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    Limited Competition: Advancing the Science of Complementary and Integrative Health Approaches to Improve Maternal Health Outcomes (R01 Clinical Trial Required)

    This grant funds studies testing complementary and integrative approaches to improve maternal health outcomes, specifically targeting currently funded NIH investigators.

    This grant is no longer accepting proposals

    National Institutes of Health has archived this opportunity.

    Funder: National Institutes of Health

    Due Dates: April 5, 2025 (Letter of Intent) | May 5, 2025 (Application)

    Funding Amounts: Up to $350,000 direct costs/year for up to 3 years; total program funding ~$1.5M; up to 3 awards expected.

    Summary: Funds multi-site feasibility clinical trials of complementary and integrative (mind and body) interventions to improve maternal health, limited to current NIH IMPROVE Initiative investigators.

    Key Information: Only currently funded IMPROVE Initiative investigators are eligible; non-U.S. organizations are not eligible.


    Description

    This limited competition opportunity supports multi-site feasibility clinical trials of complementary and integrative health approaches—specifically mind and body interventions—to promote healthy pregnancies and improve maternal health outcomes. The program is part of the NIH IMPROVE Initiative, which addresses the U.S. maternal health crisis, with a focus on reducing disparities and building evidence for nonpharmacologic interventions. The goal is to generate critical feasibility data necessary for planning future, fully powered efficacy or effectiveness trials.

    Eligible applicants must be currently funded investigators under the NIH IMPROVE Initiative. Projects should test the feasibility of delivering mind and body interventions (e.g., yoga, mindfulness, acupuncture, meditation, tai chi, massage, etc.) across multiple, geographically distinct sites, and address key process outcomes such as recruitment, retention, intervention fidelity, and data collection.


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