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    DoD Breast Cancer Breakthrough Award Levels 1 and 2

    DoD grant supports breast cancer research breakthroughs at two funding levels, focusing on major impact and addressing specific challenges, with options for single or partnering PIs.

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    Early Career Research Grants for New FacultyCancer Research Grants 2026

    This grant is no longer accepting proposals

    Dept. of the Army -- USAMRAA has archived this opportunity.

    Funder: Dept. of the Army -- USAMRAA

    Due Dates: June 13, 2025 (Pre-application/LOI) | June 27, 2025 (Full application)

    Funding Amounts: Up to $750,000 (Level 1, single PI, 3 yrs) | Up to $1.65M (Level 2, single PI, 3 yrs) | Up to $2.5M (Level 2, Population Science & Prevention, single PI, 4 yrs); higher for Partnering PI Option; ~20 awards, total $33.7M

    Summary: Supports high-impact research with potential for breakthroughs in breast cancer, addressing at least one FY25 Breast Cancer Research Program overarching challenge.

    Key Information: Clinical trials are not allowed; both pre-application and full application are required.


    Description

    This opportunity supports innovative, high-impact research aimed at making significant breakthroughs in breast cancer. Projects must address at least one of the FY25 Breast Cancer Research Program (BCRP) overarching challenges, with the potential to fundamentally change prevention, diagnosis, or treatment of breast cancer. The Breakthrough Award Levels 1 and 2 are designed for research at different stages, from high-risk, early-stage ideas (Level 1) to projects with substantial preliminary data supporting clinical translation (Level 2). A special option exists for population science and prevention studies at Level 2.

    Key features include:

    • Multiple funding levels to match research maturity and scope.
    • Option for single or two partnering Principal Investigators (PIs).
    • Emphasis on projects with potential for major, not incremental, impact.
    • Population science and prevention studies may request higher funding and longer duration with justification.
    • Clinical trials are not permitted under this mechanism.

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