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    Accelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens

    This grant supports researchers analyzing All of Us biospecimens to study biomarkers and chronic diseases, contributing new data to advance precision medicine and broaden research resources.

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    Funder: National Institutes of Health

    Due Dates: March 1, 2027

    Funding Amounts: No funds provided; X01 resource access only (no direct monetary award)

    Summary: Supports partnered research using All of Us Biobank biospecimens to advance precision medicine and add new data to the All of Us dataset.


    Description

    This opportunity enables researchers to access stored blood plasma, blood serum, and extracted DNA from the All of Us Research Program Biobank. The goal is to accelerate health research and medical breakthroughs by enabling individualized prevention, treatment, and care. Funded studies—through the X01 mechanism—are collaborative partnered research projects that add new data to the All of Us Researcher Workbench, following program best practices.

    Projects may include multiomics analyses (genomics, proteomics, metabolomics), early disease detection, biomarker discovery or validation, novel risk models for disease, and disease stratification for chronic disease risk, diagnosis, or prognosis. The program supports longitudinal follow-up, repeat sampling, and integration with clinical, environmental, and life-course data, and is open to the broad scientific community.


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