Addressing Health Outcomes for Individuals With Intellectual and Developmental Disabilities (IDD) and/or Rare Diseases (RD) PCORI Funding Announcement
PCORI funds research comparing interventions to improve health outcomes and care for individuals with intellectual and developmental disabilities and/or rare diseases.
Funder: Patient-Centered Outcomes Research Institute
Due Dates: September 9, 2026 (Letter of Intent) | January 12, 2027 (Full Application)
Funding Amounts: Up to $12 million direct costs per award; project period up to 5 years.
Summary: Supports comparative clinical effectiveness research to improve health outcomes for individuals with intellectual and developmental disabilities and/or rare diseases, including patient-centered care, care transitions, interventions, and caregiver support.
Key Information: LOI required; projects may focus on either IDD or RD populations (or both).
Description
This Patient-Centered Outcomes Research Institute (PCORI) funding opportunity aims to support high-impact, patient-centered comparative clinical effectiveness research (CER) projects focused on people living with intellectual and developmental disabilities (IDD) and/or rare diseases (RD). The initiative seeks to address significant gaps in evidence by funding studies that improve health outcomes, quality of life, care transitions, and caregiver well-being for these populations. Research may focus on comparing strategies for patient-centered care, effective interventions (pharmacologic or nonpharmacologic), health system approaches, and support for caregivers. Projects are expected to meaningfully engage patients and stakeholders throughout the research process and deliver clinically meaningful outcomes.
