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    ancient DNA for Modern Genomics (aDMG) Research Projects (U01 Clinical Trials Not Allowed)

    Forecasted

    NHGRI will fund projects using ancient human DNA to better understand modern human diseases and traits by integrating ancient and modern genomic data, encouraging collaboration across genomics and related fields.

    Funder: National Institutes of Health

    Due Dates (Anticipated): February 2028 (Full application deadline, projected)

    Funding Amounts: Not specified; award size and ceiling TBD. Cooperative Agreement (U01 mechanism).

    Summary: Supports research leveraging ancient and historical human DNA to advance understanding of modern human traits, diseases, and biology by integrating ancient DNA with contemporary genomics data.

    Key Information: This is a forecasted opportunity; details and deadlines are subject to change.


    Description

    The National Human Genome Research Institute (NHGRI) at NIH plans to launch a funding opportunity for research projects under the ancient DNA for Modern Genomics (aDMG) program. The initiative aims to develop an ethical and comprehensive resource of ancient and historical human DNA (aDNA) data to inform studies on contemporary human traits, biology, and health. The program seeks applications that will leverage both existing and newly generated aDNA data, integrating it with modern human and other species’ data to deepen biological and epidemiological insights into modern diseases and health-related traits. Collaborative, interdisciplinary approaches—combining expertise in DNA sequencing, computational genomics, data science, human evolution, and ancient populations—are especially encouraged. This opportunity will use the U01 cooperative agreement mechanism.


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