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    Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)

    This grant will fund centers that develop, maintain, and share animal models, biological materials, and new research methods to support biomedical research and improve scientific rigor and reproducibility.

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    Funder: National Institutes of Health

    Due Dates: September 26, 2028

    Funding Amounts: Estimated total funding $1,300,000; expected 2 awards; award size/duration not specified

    Summary: Supports resource centers providing laboratory animals, biological materials, and related services to enhance rigor and reproducibility in biomedical research.

    Key Information: Foreign organizations and components are not eligible to apply.


    Description

    This funding opportunity supports the establishment or continuation of Animal and Biological Material Resource Centers, which provide specialized colonies of laboratory animals, biological materials (such as cells, tissues, organs, and genetic stocks), and associated services. These Centers serve the biomedical research community at local, regional, and national levels, aiming to optimize scientific rigor, transparency, and reproducibility. The Centers are expected to have broad utility across multiple NIH Institutes or Centers and align with the Office of Research Infrastructure Programs (ORIP) NIH-wide mission.

    The initiative also emphasizes integrating new approach methodologies (NAMs)—including cell culture, organoids, computational models, and microphysiological systems—to complement traditional animal-based research. Applicants should design an applied research component to generate comparative data and promote the integration of predictive human disease models. Consulting with NIH scientific/research staff before applying is strongly recommended to ensure alignment with program priorities and competitiveness.


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