Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)
NCI invites studies on how bariatric surgery affects cancer risk to attract researchers focusing on long-term cancer effects, not just weight loss or diabetes outcomes.
Funder: National Institutes of Health
Due Dates: May 6, 2025 (Letter of Intent) | June 5, 2025 (New) | July 5, 2025 (Renewal/Resubmission/Revision) | October 5, 2025 (New) | November 5, 2025 (Renewal/Resubmission/Revision) | February 5, 2026 (New) | March 5, 2026 (Renewal/Resubmission/Revision) | June 5, 2026 (New) | July 5, 2026 (Renewal/Resubmission/Revision) | October 5, 2026 (New) | November 5, 2026 (Renewal/Resubmission/Revision) | February 5, 2027 (New) | March 5, 2027 (Renewal/Resubmission/Revision) | June 5, 2027 (New) | July 5, 2027 (Renewal/Resubmission/Revision) | October 5, 2027 (New) | November 5, 2027 (Renewal/Resubmission/Revision)
Funding Amounts: Up to $500,000 direct costs per year, for a maximum project period of 5 years.
Summary: Supports investigator-initiated studies on the biological mechanisms by which bariatric surgery impacts cancer risk, emphasizing mechanistic over short-term metabolic outcomes.
Key Information: Clinical trial proposals are allowed but must include a bariatric surgeon as a key investigator; epidemiologic-only studies are not responsive.
Description
This opportunity, issued by the National Cancer Institute (NCI) at NIH, invites applications for research projects investigating the mechanisms by which bariatric surgery influences cancer risk. The goal is to attract researchers who study bariatric surgery to focus on long-term cancer outcomes and underlying biological mechanisms, rather than short-term endpoints such as weight loss or diabetes improvement.
The program supports both animal and human studies, or a combination, provided the research is mechanistically focused and links bariatric surgery to cancer endpoints. Projects may include clinical trials, provided a bariatric surgeon is a key investigator. Applications that are solely epidemiological or focus only on in vitro studies are not responsive.
