BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iTeamBCP (RM1 Clinical Trial Optional)
This grant will fund collaborative teams to uncover how brain circuits produce mental experiences and behavior by integrating cellular, circuit, and behavioral analyses using innovative, multi-disciplinary neuroscience approaches.
Funder: National Institutes of Health
Due Dates: June 16, 2026 (Estimated)
Funding Amounts: Award size and total funding not yet specified; RM1 mechanism; multi-year, multi-investigator team projects expected
Summary: Supports integrative, team-based research to uncover fundamental principles of central nervous system function across cells, circuits, and behavior.
Key Information: Forecasted opportunity; details subject to change—check for updates.
Description
The National Institutes of Health, led by the National Institute of Neurological Disorders and Stroke (NINDS) and several partner institutes, intends to solicit applications for large, multi-investigator team projects aimed at understanding how the nervous system generates mental experience and behavior. The program seeks to bridge different levels of central nervous system (CNS) analysis—cellular, circuit, and behavioral—using integrative approaches.
Teams must include 3–6 PDs/PIs with distinct and complementary expertise. Projects must:
- Integrate large-scale information about circuit components (e.g., cell types, connectivity)
- Incorporate in vivo CNS recordings at cellular and sub-second temporal resolution
- Analyze tractable behaviors or well-defined neural systems
Tool development to surmount key research roadblocks is encouraged. Experimental systems should be chosen for their ability to reveal generalizable, multi-scale principles about CNS computations. Collaborative teams, including those with expertise in molecular, cellular, systems, computational, and theoretical neuroscience, as well as engineering, data science, mathematics, physics, and statistics, are encouraged to apply.
