Breakthrough T1D Request for Applications: Studies addressing clinically relevant questions about ketones and the use of continuous ketone monitoring in type 1 diabetes
Supports research using continuous ketone monitoring to advance understanding and clinical management of type 1 diabetes, aiming to prevent complications and improve patient outcomes.
Funder: Breakthrough T1D
Due Dates: November 12, 2025 (Letter of Intent) | January 21, 2026 (Full proposal)
Funding Amounts: Up to $1,500,000 total over 3 years; larger budgets considered with strong justification.
Summary: Supports research using continuous ketone monitoring to address clinically relevant questions and improve outcomes in type 1 diabetes.
Description
This grant opportunity from Breakthrough T1D seeks studies that utilize continuous ketone monitoring (CKM) to address clinically relevant questions about ketone dynamics in type 1 diabetes (T1D). The aim is to leverage advanced CKM technology to gain new insights into T1D pathophysiology, improve prevention of diabetic ketoacidosis (DKA), and enhance the quality of life for people with T1D. Research may explore the clinical significance of ketone patterns, integration of CKM with other diabetes management tools, educational strategies, and prediction or prevention of acute and long-term complications. Both interventional clinical trials and observational studies are supported, with an emphasis on innovative, clinically translatable findings.
