[National Institutes of Health](https://www.nih.gov)

January 2027

Five U01 cooperative agreements anticipated; specific award size not stated; multi-year support expected.

Supports canine cancer immunotherapy clinical trials and network coordination to inform and advance human cancer treatments.

--- ## Description This opportunity aims to advance cancer immunotherapy research by supporting clinical trials in pet dogs with spontaneously occurring cancers, leveraging their similarities to human disease progression and treatment response. The program will fund a network (K9CIN) consisting of five U01 cooperative agreements: one Network Coordinating Center (with limited research activities) and four sites conducting canine clinical trials using immunotherapeutic agents alone or in combination with other treatments. The results are intended to inform both canine health and translational research for human cancer therapies. This reissue consolidates previous funding mechanisms to streamline support for the network and encourages applications for both the coordinating center and clinical trial sites. --- ## Due Dates - January 2027 (anticipated/projected) *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - A total of five U01 cooperative agreements are anticipated: one for the Network Coordinating Center and four for clinical trial sites. - Specific award ceilings or total program funding are not stated in the forecast; multi-year support is expected. --- ## Eligibility Eligible applicants include: - State, county, city, or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (federally recognized and other) - Public housing authorities/Indian housing authorities - Nonprofits (with or without 501(c)(3) status), other than institutions of higher education - Private institutions of higher education - For-profit organizations (including small businesses) - U.S. territories or possessions - Faith-based or community-based organizations - Regional organizations - Eligible agencies of the federal government - Non-domestic (non-U.S.) entities (foreign institutions) Applicants may apply for either the Network Coordinating Center (with limited research focus) or for conducting canine cancer immunotherapy clinical trials and correlative studies. --- ## Application Process - Applications will be submitted through [Grants.gov](https://www.grants.gov/search-results-detail/361532) when the opportunity opens. - Carefully review the program forecast and check for the official Notice of Funding Opportunity (NOFO) when released. - Prepare to address the specific focus: either as a coordinating center or as a clinical trial site. - No cost sharing or matching is required. --- ## Additional Information - The program is intended to maintain momentum in canine immunotherapeutic development, including the evaluation of novel and repurposed drugs, treatment combinations, and dosing strategies. - Results from these canine trials are expected to be highly translatable to human cancer research. - The NOFO consolidates prior funding opportunities to streamline the application process and support the continued growth of the K9CIN. --- ## External Links - [NIH Funder Page](https://www.nih.gov) - [Grants.gov Forecast Opportunity](https://www.grants.gov/search-results-detail/361532) --- ## Contact Information | Contact | Email | Phone | |------------------------|-----------------------------------------|--------------| | NCI K9CIN Program Team | [K9CIN_Grants@mail.nih.gov](mailto:K9CIN_Grants@mail.nih.gov) | 240-276-7187 | ---

Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)

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