[Marfan Foundation](https://www.marfan.org)

October 2026 (application deadline, projected)

$100,000 total over two years ($50,000/year); no indirect costs allowed

Supports early-career investigators conducting basic, translational, or clinical research on Marfan syndrome, Loeys-Dietz syndrome, Vascular Ehlers-Danlos syndrome, and related conditions.

This is a forecasted opportunity—dates are projected and may change.

--- ## Description This grant supports early-career researchers working on Marfan syndrome, Loeys-Dietz syndrome, Vascular Ehlers-Danlos syndrome (VEDS), and related genetic aortic and vascular conditions. The aim is to provide investigators with preliminary data in high-impact areas, increasing their competitiveness for future funding from major agencies such as NIH or EU. Projects may be basic, translational, or clinical research and can focus on cardiovascular, orthopedic, pulmonary, pain, ophthalmologic, or other relevant disciplines. Innovative approaches, including novel animal models, DNA/RNA technologies, artificial intelligence, and interdisciplinary collaborations, are encouraged. --- ## Due Dates - October 2026: Application deadline (anticipated/projected, based on prior cycles) *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - Total award: $100,000 over two years ($50,000 per year) - No institutional overhead or indirect costs permitted - Funds may be used for salaries (PI, support personnel, postdocs), supplies, and project-related expenses, but not for major equipment, office furniture, travel (unless required for the project), tuition, or administrative salaries. --- ## Eligibility - Principal Investigator (PI) must hold an MD, DO, PhD, ScD, DDS, DVM, or equivalent. - PI must have less than seven years of experience in a faculty position (excluding clinical house staff/fellowship training). - PI must not have received an NIH R01 or equivalent grant; prior R01 holders are ineligible. - Cannot hold an NIH K or other training grant concurrently with this award. - Only one Career Development Award can be received from the Marfan Foundation within the seven-year eligibility window. - Open to applicants worldwide (U.S. and international institutions eligible). - Proven ability to conduct independent research, evidenced by original research publications, is required. - For clinical studies, applicants must have access to appropriate patient populations. --- ## Application Process - Applications must be submitted electronically as a single PDF via the [Marfan Foundation application portal](http://www.tfaforms.com/4773381). - Required sections include: - Title page (with signatures) - Table of contents - Project abstract (300 words max) and lay summary (500 words max) - Research plan (3 pages max) - Budget and justification (detailed, with no indirect costs) - Other support (current and pending grants) - Biographical sketches (NIH format or supplied form, 5 pages max per key personnel) - Facilities description (1 page) - Appendix (figures, tables, literature cited, IRB/IACUC approvals, letters of support) - IRB/IACUC approvals (or pending status) must be included for studies involving human or animal subjects. - Progress and financial reports are required at 10 months and at grant completion. - Intellectual property provisions apply (see guidelines for details). --- ## Additional Information - Proposals are evaluated by the Marfan Foundation Scientific Advisory Board using an NIH-style peer review process. - The award is contingent on Board of Directors approval. - The Foundation reserves the right to use the PI's name and likeness in publicity related to the award. - Publications resulting from funded work must acknowledge the Foundation and be reported back to them. --- ## External Links - [Marfan Foundation Grants Program Overview](https://marfan.org/research/grants/) - [Career Development Award Program Page](https://marfan.org/resource-library/career-development-award/) - [Download Grant Guidelines (PDF)](https://marfan.org/wp-content/uploads/2025/03/CAREER-DEVELOPMENT-AWARD-GUIDELINES_24Jul2025.pdf) - [Download Application Forms (PDF)](https://marfan.org/wp-content/uploads/2021/07/CareerDev.en_rev.pdf) - [Submit Application Online](http://www.tfaforms.com/4773381) --- ## Contact Information | Name | Title | Email | Phone | |---------------------------|------------------------|---------------------|------------------------| | Lauren May, MPH | Director of Research | lmay@marfan.org | Not listed | | Josephine Grima, PhD | Chief Science Officer | jgrima@marfan.org | 800-8-MARFAN / 516-883-8712 ext. 117 | For general inquiries, you may also use the [Marfan Foundation contact page](https://www.marfan.org/contact).

Career Development Award

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