Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)
Limited submission
This grant provides a 3-year extension for COPE-AKI clinical centers to complete enrollment, follow-up, and data analysis to improve care for patients after acute kidney injury.
Funder: National Institutes of Health
Due Dates: November 6, 2026 (Application)
Funding Amounts: $1.85 million in FY2027 direct costs for approximately 3 awards; maximum project period 3 years
Summary: Supports continuation of the COPE-AKI clinical centers to complete trial enrollment, participant follow-up, analysis, and dissemination.
Key Information: Limited competition: only current recipients under RFA-DK-20-011 are eligible.
Description
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of NIH, supports continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) clinical centers through U01 cooperative agreements. This renewal opportunity provides up to three additional years to meet enrollment targets, complete participant follow-up, analyze data, and disseminate findings within the existing consortium of three clinical centers and one Scientific and Data Research Center (SDRC).
COPE-AKI is a randomized controlled trial testing a multimodal process-of-care intervention against usual care after hospitalization with Stage 2 or 3 acute kidney injury. The intervention aims to reduce rehospitalization and morbidity. Because there is currently no standard of care for patients after hospitalization with AKI, successful completion is expected to inform improved clinical management and development of a standard of care for survivors.
