RFA: Common Mechanisms in Autoimmunity Insight Awards
Funds one-year pilot projects investigating shared and unique immune mechanisms in type 1 diabetes, multiple sclerosis, and lupus to advance understanding and foster innovative therapies across these autoimmune diseases.
Funder: Breakthrough T1D
Due Dates (Anticipated): January 2027 (Full proposal/application deadline; projected)
Funding Amounts: Up to $150,000 for 1 year (includes up to 10% indirect costs)
Summary: Funds proof-of-concept research into common and distinct immune mechanisms of autoimmune diseases to foster collaboration and advance innovative therapies across multiple conditions.
Key Information: Projects must address mechanisms relevant to at least two of: type 1 diabetes, multiple sclerosis, or lupus.
Description
This opportunity, offered collaboratively by Breakthrough T1D, the Lupus Research Alliance, and the National Multiple Sclerosis Society, supports one-year pilot projects investigating the shared and distinct immune mechanisms underlying autoimmune diseases. The program seeks to advance understanding of autoimmune pathogenesis, validate therapeutic targets, or provide proof-of-concept for innovative therapeutic strategies relevant to multiple autoimmune diseases—especially type 1 diabetes (T1D), multiple sclerosis (MS), and systemic lupus erythematosus (SLE). Proposals should lay the groundwork for larger, multi-year studies by addressing key knowledge gaps and fostering new approaches to treating or curing autoimmune conditions. Cross-disciplinary collaboration and the use of human samples or data are strongly encouraged.
