Cooperative Program for Modeling Clinical Transplantation
This grant funds development of innovative lab and animal models to improve human organ transplantation, focusing on clinically relevant, translatable systems that reduce animal use and support data sharing for better outcomes.
Funder: National Institutes of Health
Due Dates (Anticipated): October 2026 (Full application deadline, projected)
Funding Amounts: Estimated total program funding: $1,280,000; ~3 awards expected; typical duration and ceiling not specified.
Summary: Supports innovative, clinically translatable models to advance new therapeutics and improve outcomes in human solid organ transplantation.
Key Information: This is a forecasted opportunity—dates and details are subject to change; check the program page for updates.
Description
The National Institute of Allergy and Infectious Diseases (NIAID) anticipates supporting research through a cooperative agreement focused on modeling clinical transplantation. The program seeks to accelerate the translation of new therapies for human solid organ transplantation by supporting development and refinement of innovative in-vitro and in-vivo models. Projects may use new approach methods (NAMs) such as immune-competent microphysiological systems, organoids, ex-vivo perfused human organs, precision-cut tissue slices, and computational systems biology models. Applicants should propose models that address current barriers to clinical translation, reduce reliance on nonhuman primates, and demonstrate relevance to clinical outcomes. Emphasis is placed on data sharing, reproducibility, and establishing best practices in the field.
