Funder: Centers for Disease Control - NCIPC
Due Dates: May 5, 2025 (Application) | March 26, 2025 (Informational call)
Funding Amounts: Up to $125,000 per year for up to 5 years; 100% non-federal match required.
Summary: Supports new community coalitions in the U.S. to prevent and reduce youth substance use through multi-sector collaboration and evidence-based strategies.
Key Information: Only coalitions that have never received DFC funding are eligible; strict eligibility and documentation requirements apply.
Description
This opportunity funds new community-based coalitions to prevent and reduce substance use among youth (18 years and younger) by supporting collaborative, evidence-based strategies at the local level. The program is administered by the CDC’s National Center for Injury Prevention and Control (NCIPC) in partnership with the Office of National Drug Control Policy (ONDCP). The grant aims to:
- Establish and strengthen collaboration among communities, public and private non-profit agencies, and all levels of government.
- Reduce substance use among youth and, over time, among adults by addressing risk and protective factors in the community.
Coalitions must be newly applying (never previously funded by DFC) and must demonstrate broad, multi-sector engagement and a comprehensive approach to youth substance use prevention.
Due Dates
- Application Deadline: May 5, 2025, 11:59 p.m. ET (via Grants.gov)
- Informational Webinar: March 26, 2025, 2–4 p.m. ET (recording available for later viewing)
- Expected Award Date: August 29, 2025
- Expected Start Date: September 30, 2025
Funding Amount
- Award Ceiling: Up to $125,000 per year
- Project Period: Up to 5 years (five 12-month budget periods)
- Total Program Funding: Approx. $31,250,000 over 5 years
- Number of Awards: ~50 expected
- Cost Sharing/Match: 100% non-federal match required (cash or in-kind; opioid settlement funds may be used if allowed by law)
Eligibility
Eligible applicants must:
- Be a community-based coalition that has never received DFC funding.
- Be a 501(c)(3) nonprofit or partner with an eligible fiscal agent (e.g., state/local/tribal government, school district, higher education, other nonprofit, or for-profit entity).
- Reside within the U.S. or U.S. territories.
- Meet all DFC statutory eligibility requirements, including:
- Representation from 12 required community sectors (e.g., youth, parents, business, media, schools, law enforcement, healthcare, etc.).
- Coalition must have existed for at least 6 months prior to application.
- Mission statement focused on youth substance use prevention.
- Address at least two substances in the action plan.
- No overlap in service area with another DFC-funded coalition (unless a letter of mutual cooperation is provided).
- Not have received more than 10 years of DFC funding (for any coalition, including under different fiscal agents).
- Be able to participate in the DFC National Cross-Site Evaluation.
- Request no more than $125,000/year and provide a 100% non-federal match.
Ineligible:
- Coalitions or fiscal agents that have already received 10 years of DFC funding.
- Organizations proposing research activities.
- Organizations in a different state than the coalition.
- Organizations with an active DFC grant.
Application Process
- Register Early: Ensure active registrations with both SAM.gov and Grants.gov (can take several weeks).
- Prepare Required Documents:
- Project abstract (1 page)
- Project narrative (20 pages max)
- Budget and budget narrative (with 100% match)
- Attachments (see below)
- Required Attachments:
- Sector table (12 required sectors)
- Coalition meeting minutes (showing 6+ months existence)
- General applicant information (key personnel, mission, community data)
- Letter of mutual cooperation (if ZIP code overlap)
- Statement of legal eligibility (501(c)(3) or fiscal agent)
- Memorandum of Understanding (if using a fiscal agent)
- Assurance of 10-year funding limit
- Disclosure of prior DFC funding
- Congressional notification
- Indirect cost rate agreement (if applicable)
- Resumes/job descriptions for key personnel
- Report on overlap (if applicable)
- Submit via Grants.gov: Search for opportunity number CDC-RFA-CE-25-0114. Only one application per organization UEI is allowed.
- Review Process: Applications are screened for eligibility, then scored on narrative criteria (background, approach, work plan, evaluation, capacity, collaborations).
- Post-Award Requirements: Annual performance and financial reports, participation in required training (including National Coalition Academy), and ongoing compliance with eligibility.
Additional Information
- Matching Funds: Must match federal funds 1:1 with non-federal sources (cash or in-kind). Opioid settlement funds may be used if not otherwise federally funded.
- Unallowable Costs: No research, clinical care, equipment/furniture purchases, law enforcement equipment, stipends, or unproven curricula. No pass-through funding to other organizations.
- Key Personnel: Must include an Authorized Organization Representative (AOR), Program Director/Principal Investigator (PD/PI), and Project Coordinator (AOR and PD/PI must be different individuals).
- Evaluation: Participation in the DFC National Cross-Site Evaluation is mandatory, including biennial data collection on core measures (alcohol, tobacco, marijuana, prescription drugs) for at least three grades (6–12).
- Training: Year 1 recipients must attend the National Coalition Academy.
External Links
Contact Information