An evidence-based clinical practice guideline for dental pain (surgical and non-surgical)

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Description

This grant opportunity was issued by the Food and Drug Administration (FDA) under the Department of Health and Human Services to support the development of an evidence-based clinical practice guideline (CPG) for dental pain management, including both surgical and non-surgical pain. The initiative aligns with Section 3002 of the SUPPORT Act (signed into law in October 2018), which mandates the FDA Commissioner to develop opioid analgesic prescribing guidelines for acute pain treatment where none currently exist.

The FDA contracted the National Academies of Science, Engineering, and Medicine (NASEM) to create a framework for these guidelines. In December 2019, NASEM identified dental surgeries (such as third molar extraction) and dental pain as priority areas due to their high prevalence, the affected patient populations (notably adolescents and young adults), and existing evidence supporting nonopioid pain management strategies.

The grant aims to fund projects that will:

• Develop evidence-based clinical practice guidelines for dental pain.
• Disseminate and implement these guidelines effectively.
• Monitor and evaluate the uptake and impact of the guidelines on opioid prescribing practices.

This effort is part of a broader public health strategy to reduce opioid prescriptions and improve pain management practices in dental care.

Due Dates

• This funding opportunity is archived with the original application deadline on May 26, 2021.
• No current or future deadlines are available.

Funding Amount

• The announcement does not specify a funding ceiling or floor.
• The funding instrument is a Cooperative Agreement, indicating substantial FDA involvement.
• Only one award was expected under this opportunity.

Eligibility

Eligible applicants include a wide range of organizations:

• State, county, city or township, and special district governments
• Native American tribal governments (both federally recognized and others)
• Public and private institutions of higher education (including HBCUs, Hispanic-serving institutions, tribal colleges, and others)
• Nonprofits with or without 501(c)(3) status (excluding institutions of higher education)
• For-profit organizations other than small businesses
• Small businesses
• Independent school districts
• Public housing authorities/Indian housing authorities
• Faith-based or community-based organizations
• Regional organizations
• Others as specified in the full announcement

Application Process

• The original application process was managed through Grants.gov.
• Applicants were required to submit proposals addressing the development, dissemination, implementation, and evaluation of the dental pain clinical practice guideline.
• No cost sharing or matching funds were required.

Additional Information

• The grant supports the FDA’s mission to improve public health by reducing opioid misuse through evidence-based prescribing guidelines.
• The NASEM consensus report serves as a foundational document guiding the research priorities and framework for guideline development.
• The focus on dental pain is due to its high incidence in emergency departments and the documented effectiveness of nonopioid pain management strategies.
• The grant encourages establishing processes for monitoring the impact of guidelines on prescribing behavior.

External Links

• FDA Home Page
• Grant Opportunity on Grants.gov
• FDA Contact Page

Contact Information