Assessing the Feasibility of Incorporating Mechanisms in Multisite Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R01 Clinical Trial Required)
This grant will fund multisite feasibility studies testing whether mind and body interventions like meditation or yoga can be reliably delivered and measured for their effects on whole person health restoration.
Funder: National Institutes of Health
Due Dates: November 16, 2029 (Application closing date)
Funding Amounts: Award ceiling: $500,000; no cost sharing or matching required
Summary: Supports multi-site feasibility trials of mind and body interventions targeting emotional well-being mechanisms to advance whole person health research.
Key Information: Clinical trials are required; foreign applicants and foreign components are not allowed.
Description
The National Center for Complementary and Integrative Health (NCCIH), part of the National Institutes of Health, supports early-phase, multi-site feasibility trials through this R33 opportunity. The program focuses on complementary and integrative health approaches with physical and/or psychological therapeutic inputs, often called mind and body interventions. It seeks to reproduce and translate mechanisms of emotional well-being into large-scale clinical trials that advance understanding of whole person health.
Supported studies establish whether interventions can be delivered faithfully and engage targeted mechanisms reproducibly across sites. They also assess recruitment, retention, randomization, and collection of clinical and mechanistic data. Exploring relationships between changes in mechanistic targets and pooled clinical outcomes lays groundwork for rigorous clinical trials and mechanistic mediation analysis.
