[National Institutes of Health](https://www.nih.gov)

February 2027 (Full application deadline, projected)

Not yet specified; award ceiling and floor not announced (forecasted opportunity).

Supports feasibility studies necessary to inform the design and planning of future definitive clinical trials with significant public health impact.

This is a forecasted opportunity; applications are not yet being solicited.

--- ## Description The National Institutes of Health (NIH) intends to launch a funding opportunity for feasibility studies that will inform the design and conduct of future definitive clinical trials. These studies are expected to address scientific questions critical for planning subsequent efficacy, effectiveness, pragmatic, dissemination, and/or implementation trials (typically phase II or later). Proposed research should demonstrate a clear scientific necessity for feasibility work, such as evaluating recruitment, retention, randomization, intervention delivery, data collection, adherence, acceptability, or developing/adapting intervention components or protocols. Studies may utilize mixed methods and feasibility clinical trials, with the goal of enhancing the rigor and reproducibility of future trial methodologies. The ultimate aim is to enable future trials that have the potential for significant public health impact. This is a forecasted opportunity; NIH is providing this notice to allow potential applicants ample time to develop collaborations and prepare responsive projects. Investigators with expertise in clinical trial planning, design, implementation, intervention development, and/or stakeholder engagement are encouraged to consider this upcoming NOFO. --- ## Due Dates - February 2027 (anticipated/projected full application deadline) *All dates are projected based on the annual cycle; check the program page for updates.* --- ## Funding Amount - Award ceiling and floor are not yet specified for this forecasted opportunity. - Estimated total program funding and number of awards have not been announced. - Cost sharing or matching is **not required**. --- ## Eligibility Eligible applicants include: - State, county, city or township, and special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (federally recognized and other) - Public housing authorities/Indian housing authorities - Nonprofits with or without 501(c)(3) status (other than institutions of higher education) - Private institutions of higher education - For-profit organizations (including small businesses) - U.S. territories and possessions - Faith-based or community-based organizations - Regional organizations - Federal agencies - Non-domestic (non-U.S.) entities (foreign institutions) Check the official program page for the most current and detailed eligibility information when the Notice of Funding Opportunity is released. --- ## Application Process - Applications are **not being solicited at this time**; this is a forecasted opportunity. - A formal Notice of Funding Opportunity (NOFO) will be published with detailed application instructions. - Interested researchers are encouraged to begin forming collaborations and preparing project concepts in advance. --- ## Additional Information - The opportunity is managed by the NIH, specifically through the NCCIH Division of Extramural Research. - Focus is on feasibility studies that will directly inform the design of larger, definitive clinical trials. --- ## External Links - [NIH Funder Page](https://www.nih.gov) - [Forecast Listing on Grants.gov](https://www.grants.gov/search-results-detail/362101) --- ## Contact Information | Contact | Email | Notes | |----------------------------------|-----------------------------------------|----------------------------------------------------| | NCCIH Division of Extramural Research Program Officer | [NCCIHDERFunding@nih.gov](mailto:NCCIHDERFunding@nih.gov) | Please contact via e-mail for programmatic questions | ---

Feasibility Studies to Inform the Design of Future Clinical Trials

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