Fibrosis in IBD Research Initiative
Forecasted
The Fibrosis in IBD Research Initiative from the Crohn's and Colitis Foundation funds multidisciplinary research into the mechanisms and treatment targets of fibrosis in Crohn’s disease and ulcerative colitis.
Funder: Crohn's and Colitis Foundation
Due Dates (Anticipated): March 2027 (LOI) | June 2027 (LOI) | July 2027 (Full proposal) | August 2027 (Full proposal)
Funding Amounts: Up to $900,000 total over 3 years; initial $450,000 for 1.5 years, with renewal contingent on progress.
Summary: Supports translational, multidisciplinary research on mechanisms and therapeutic targets of fibrosis in IBD.
Key Information: Requires a senior PI and a junior Co-PI; open to US and international applicants.
Description
The Fibrosis in IBD Research Initiative, led by the Crohn's and Colitis Foundation (in collaboration with Takeda), funds innovative research to advance understanding of the mechanisms driving fibrosis in inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. The initiative targets the critical gap in non-surgical therapies for fibrotic complications in IBD, emphasizing projects with a translational and multidisciplinary approach. Key research areas include the pathophysiology of fibrosis, patient segmentation using multi-omics, analysis of diverse cohorts, evaluation of therapeutic targets, cellular mechanisms, and the role of the microbiome. Projects leveraging advanced datasets, biosamples, and collaborative, cross-disciplinary teams are especially encouraged.
