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    Forecast for BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)

    This grant will fund projects developing scalable technologies for mapping brain connectivity across species, as part of the BRAIN CONNECTS network, with applications opening in September 2025.

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    Funder: National Institutes of Health

    Due Dates (Anticipated): June 2026 | September 2026 | September 2025

    Funding Amounts: Award size and total funding TBD; prior rounds funded multi-year U01 projects for scalable neurotechnologies.

    Summary: Supports development of scalable methods and technologies for mapping brain connectivity across multiple scales as part of the BRAIN CONNECTS initiative.

    Key Information: This is a forecasted opportunity; all dates and details are projected and subject to change.


    Description

    This forecasted opportunity from the NIH BRAIN Initiative aims to support specialized projects developing scalable technologies for brainwide mapping of neural connectivity. The program seeks innovative approaches that can address any aspect of the connectivity mapping pipeline, including tissue processing, imaging, alignment, segmentation, annotation, error correction, and integration into neuroscience data environments. Projects may focus on humans, non-human primates, or mice, but use of other species for validation is permitted if well justified.

    Funded projects will be integrated into the BRAIN CONNECTS Network, a collaborative effort to develop technical capabilities for generating comprehensive wiring diagrams of entire brains at multiple scales. The overarching objective is to foster technology development and iterative engineering to advance our understanding of nervous system function.


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