Funder: Office of Science
Due Dates: September 30, 2026 (Full applications) | Target dates for subprograms: October 31, 2025 (Pre-apps—Electron & Scanning Probe); November 14, 2025 (Pre-apps—Inverse Methods/Quantum Computing); November 30, 2025 (Pre-apps—BES core); December 31, 2025 (Full—Electron & Scanning Probe); February 1, 2026 (Full—BES core); January 16 & 28, 2026 (Full—ASCR panels)
Funding Amounts: $50,000–$5,000,000 per award; most project periods 3 years; up to $500M total program funding; ~200–350 new awards/year.
Summary: Annual open call for basic research proposals in all DOE Office of Science mission areas, including computing, energy, materials, environment, physics, and isotope R&D.
Key Information: Unrestricted eligibility (except DOE/NNSA labs as lead); pre-applications encouraged; multiple topic-specific deadlines apply.