GBA1 Parkinson's Disease Research Catalyst Program
Supports integrative, cross-cohort research to uncover molecular mechanisms and modifiers of GBA1-associated Parkinson’s disease, with a focus on open data sharing and systematic disease model characterization.
Funder: Michael J. Fox Foundation for Parkinson's Research
Due Dates (Anticipated): May 2027: Pre-proposal/pre-application deadline (projected)
Funding Amounts: Amount not specified; award size commensurate with proposed work and project scope.
Summary: Supports integrative, cross-cohort research to advance understanding of GBA1-associated Parkinson’s disease mechanisms and variability.
Key Information: Open Science Policy applies—grantees must share data, code, and outputs openly.
Description
The GBA1 Parkinson's Disease Research Catalyst Program is designed to accelerate the biological understanding of GBA1-associated Parkinson’s disease (GBA1-PD). The program supports hypothesis-driven projects that emphasize integrative, cross-cohort analyses and systematic characterization of disease models. Funded research should focus on elucidating molecular mechanisms linking GBA1 dysfunction to neurodegeneration, identifying modifiers of disease variability, and characterizing cell-type–specific and systems-level effects of GBA1 dysfunction. Priority is given to proposals that integrate data across cohorts and modalities, leverage and enhance existing datasets or resources, and include robust plans for validation, standardization, and open data sharing.
