The Genesis Mission: Transforming Science and Energy with AI
The Department of Energy seeks interdisciplinary teams to use AI for advancing science, energy, and technology in areas like manufacturing, biotech, critical materials, and nuclear research.
Funder: Office of Science
Due Dates: May 1, 2026 (Phase I applications & Phase II Letters of Intent) | May 19, 2026 (Phase II full applications) | December 17, 2026 (Phase II applications from FY26 Phase I awards; final closing)
Funding Amounts: Phase I: $500,000–$750,000 (9 months); Phase II: typically 3–5× Phase I per year (up to $16M total, 3 years); total program: $293.76M.
Summary: Supports interdisciplinary teams to accelerate DOE science, energy, and national security missions using novel artificial intelligence models and frameworks.
Key Information: Multi-institutional teams required; cost share required for for-profit and demonstration projects; foreign entities generally ineligible.
Description
This funding opportunity from the U.S. Department of Energy (DOE) Office of Science seeks interdisciplinary teams to address the Genesis Mission National Science and Technology Challenges by accelerating scientific discovery and research workflows using novel artificial intelligence (AI) models and frameworks. The program aims to advance DOE’s mission in energy, environment, and national security, leveraging the scientific and data resources of the DOE, National Laboratories, U.S. industry, and academia. Projects may span advanced manufacturing, biotechnology, critical materials, nuclear fission and fusion, quantum information science, semiconductors, microelectronics, discovery science, and energy. Successful AI models and workflows may be integrated into the American Science Cloud.
