Discovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)
NIH seeks applications to submit pediatric cancer or congenital anomaly samples for genomic and related sequencing to uncover genetic causes, with data shared via the Kids First Data Resource Center.
Funder: National Institutes of Health
Due Dates: July 19, 2026 (Estimated application due date) | January 11, 2027 (Final application deadline)
Funding Amounts: No specified ceiling or floor; funding amount varies by project scope and NIH resources.
Summary: Supports genomic and related molecular studies of pediatric cancer and congenital anomaly cohorts to elucidate genetic contributions and expand the Kids First Data Resource.
Key Information: This is a forecasted opportunity; foreign organizations are not eligible to apply.
Description
This opportunity, part of the Gabriella Miller Kids First Pediatric Research Program, invites applications to submit samples from pediatric cohorts for whole genome sequencing and related molecular assays at NIH-supported centers. The program aims to advance understanding of the genetic basis of childhood cancers and congenital anomalies, including the molecular links between congenital anomalies and increased cancer risk. Applicants may propose sequencing (whole genome, exome, transcriptome), proteomics, and epigenomic assays, provided these are justified by the research aims. All resulting data and associated clinical/phenotypic information will be integrated into the Kids First Data Resource Center for broad sharing with the research community.
