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    Discovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)

    NIH seeks applications to submit pediatric cancer or congenital anomaly samples for genomic and related sequencing to uncover genetic causes, with data shared via the Kids First Data Resource Center.

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    Funder: National Institutes of Health

    Due Dates (Anticipated): July 2026

    Funding Amounts: No set award ceiling or floor; supports whole genome and related sequencing projects for pediatric cohorts.

    Summary: Supports submission and sequencing of pediatric cancer and congenital anomaly cohorts to elucidate genetic bases and expand the Kids First Data Resource.

    Key Information: This is a forecasted opportunity; dates and details may change.


    Description

    The National Institutes of Health (NIH), through the Gabriella Miller Kids First Pediatric Research Program, anticipates inviting applications to submit samples from pediatric cohorts for comprehensive genomic and related molecular analyses at a Kids First-supported sequencing center. The goal is to advance understanding of the genetic contributions to childhood cancers and congenital anomalies, uncover associations between congenital anomalies and cancer risk, and broaden the range of pediatric disorders represented in the Kids First Data Resource. Supported activities include whole genome, exome, and transcriptome sequencing, as well as long-read sequencing, proteomics, and epigenomic assays when scientifically justified. All generated data, along with relevant clinical and phenotypic information, will be made available to the research community via the Kids First Data Resource Center.


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