Advancing Global Health
This grant supports projects that advance the America First Global Health Strategy by saving lives, strengthening health systems, and ensuring U.S. investments benefit American safety and prosperity.
Funder: Bureau of Global Health Security and Diplomacy
Due Dates: May 31, 2026 (APS Window 1) | July 31, 2026 (APS Window 2a) | September 15, 2026 (APS Window 2b & Addenda G/H/I/J) | October 30, 2026 (Addenda M/N) | November 14, 2026 (APS Window 3) | February 14, 2027 (Final closing)
Funding Amounts: Typical awards $500,000–$250,000,000 for up to 5 years; total program funding up to $2.1B+; addenda may have specific ceilings (e.g., $5.4M–$180M).
Summary: Supports projects advancing global health security, health system strengthening, and implementation of bilateral health MOUs through targeted, innovative, and sustainable interventions.
Key Information: Applications must respond to a specific APS Addendum; SOIs only accepted through Grants.gov or MyGrants.
Description
This opportunity, issued by the Bureau of Global Health Security and Diplomacy (GHSD) at the U.S. Department of State, seeks to advance the America First Global Health Strategy by funding projects that save lives, strengthen health systems, foster self-reliance, and enhance global and U.S. health security. The Annual Program Statement (APS) serves as an umbrella mechanism under which specific Addenda are released, each identifying priority areas, target geographies, and technical focus (e.g., disease surveillance, outbreak response, health systems integration, nutrition, NTDs, digital health, etc.).
Funding supports projects that complement or extend the implementation of bilateral Memoranda of Understanding (MOUs) between the U.S. and partner governments, as well as initiatives that address identified gaps in health systems and security. Applicants must respond to a specific Addendum, which may focus on a country, technical theme, or health system challenge.
The application process begins with a concise Statement of Interest (SOI) in response to an active Addendum. Selected SOIs may proceed to a consultative program design phase and, if invited, to a full application. Projects are expected to align with principles of country ownership, integration, sustainability, innovation, local partnership, and measurable impact.
