The Department of State seeks projects supporting the America First Global Health Strategy to save lives, strengthen health systems, and ensure U.S. health investments benefit American interests.
Funder: Bureau of Global Health Security and Diplomacy
Due Dates: May 31, 2026 (APS Window 1 SOI) | July 31, 2026 (APS Window 2a SOI; Malawi Addendum) | September 15, 2026 (APS Window 2b SOI; Cameroon, Mozambique, Cote d’Ivoire, and Survey/Surveillance Addenda) | November 14, 2026 (APS Window 3 SOI) | February 14, 2027 (APS Window 4 / Final SOI, Grants.gov closing)
Funding Amounts: Awards range from $500,000 to $250 million; up to $2.1 billion total funding; typical project period up to 5 years; multiple addenda with varying award ceilings.
Summary: Supports projects advancing the America First Global Health Strategy by strengthening health systems, improving health outcomes, and building country self-reliance through targeted addenda and partnerships.
Key Information: Submit a Statement of Interest (SOI) in response to specific Addenda; eligibility is broad and open globally.
This opportunity, managed by the U.S. Department of State’s Bureau of Global Health Security and Diplomacy (GHSD), provides a flexible, multi-window funding mechanism to advance global health security and strengthen health systems in partner countries. The program, structured as an Annual Program Statement (APS), issues a series of country- and thematic-specific Addenda that outline priority areas for investment—ranging from integrated service delivery and digital health to surveillance, outbreak response, and health system transition. Projects are expected to align with the America First Global Health Strategy, focusing on saving lives, enhancing efficiency, fostering country self-reliance, and ensuring U.S. investments contribute to American and global safety and prosperity.
Applicants submit a concise Statement of Interest (SOI) in response to a specific Addendum during one of several annual submission windows. Selected SOIs may be invited to participate in consultative program design before being invited to submit a full application. Each Addendum details its own technical focus, funding ceiling, and anticipated number of awards.