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    The Duke Endowment funds innovative, evidence-based research and programs in child well-being, health care, education, and rural churches to improve outcomes in North and South Carolina.

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    Funder: The Duke Endowment

    Due Dates: June 15, 2026 (Child & Family Well-Being pre-app) | December 15, 2026 (Child & Family Well-Being pre-app) | May 15, 2026 (Health Care pre-app) | November 15, 2026 (Health Care pre-app) | June 15, 2026 (Health Care full app) | December 15, 2026 (Health Care full app)

    Funding Amounts: No fixed minimum or maximum; in 2024, $252.9M in new grants approved across all programs, with individual awards varying by project and program area.

    Summary: Supports nonprofits and institutions in NC/SC to advance child well-being, health care, education, and rural church initiatives, with a focus on innovation and system improvement.

    Key Information: Pre-applications are required for most programs; eligibility is restricted to organizations serving North Carolina and South Carolina.


    Description

    The Duke Endowment provides significant grant funding to nonprofit organizations, academic institutions, hospitals, and churches in North Carolina and South Carolina. Its mission is to foster innovation, strengthen organizations, and support effective programs in four primary areas: Child & Family Well-Being, Health Care, Higher Education, and Rural Churches. The Endowment funds both proven and innovative approaches, with an emphasis on measurable impact and alignment with regional needs. Grantmaking is guided by the legacy of James B. Duke and focuses exclusively on the Carolinas.


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