The Duke Endowment funds innovative, evidence-based research and programs in child and family well-being and health care to drive measurable impact in North and South Carolina.
Funder: The Duke Endowment
Due Dates: November 15, 2026 (Health Care pre-app) | December 15, 2026 (Child & Family Well-Being pre-app; Health Care full app) | May 15, 2027 (Health Care pre-app) | June 15, 2027 (Child & Family Well-Being pre-app; Health Care full app)
Funding Amounts: No set minimum or maximum; typical grants range from $100,000 to several million dollars, with multi-year support possible.
Summary: Supports nonprofit organizations in North Carolina and South Carolina advancing child and family well-being, health care, education, and rural church initiatives.
Key Information: Pre-application required; only organizations in NC/SC are eligible; audited financials and accreditation often required.
The Duke Endowment provides competitive grants to nonprofit organizations in North Carolina and South Carolina, focusing on four core areas: Child & Family Well-Being, Health Care, Higher Education (for select institutions), and Rural Church. Grants are designed to support impactful programs, foster innovation, strengthen systems, and drive positive change across these sectors. The Endowment prioritizes projects with proven effectiveness, strong organizational capacity, and a commitment to measurable outcomes. They offer substantial funding to scale evidence-based models, support advocacy and policy improvements, and encourage the development of new approaches to address critical needs in the Carolinas.