GREGoRi Technology Integration Center (U01 Clinical Trials Optional)
This grant funds a center to develop standards and datasets for integrating new molecular technologies and tools to improve rare disease diagnosis.
Funder: National Institutes of Health
Due Dates: November 4, 2025 (estimated application due date, forecasted) | October 30, 2026 (application close date)
Funding Amounts: Up to $2,250,000 per award; total program funding estimated at $3,000,000; 1 award expected.
Summary: Supports establishing a center to develop standards and best practices for integrating new molecular technologies in rare disease diagnosis.
Key Information: Forecasted opportunity; final NOFO expected in 2025 with application deadline in 2026.
Description
This opportunity will fund the establishment of the GREGoRi Technology Integration Center, as part of the Genomics Research to Elucidate the Genetics of Rare Diseases: innovation (GREGoRi) initiative. The Center’s purpose is to enable the development of standards and best practices for applying new and emerging molecular methods in the diagnosis of rare genetic disorders. A major deliverable will be a multidimensional dataset to support the development and benchmarking of novel tools and strategies for rare disease diagnosis. This initiative seeks to accelerate a paradigm shift in rare disease diagnosis by leveraging innovative tools, molecular technologies, and analytical approaches to identify causal genes or variants.
