GREGoRi Innovation Projects (U01 Clinical Trial Optional)
NHGRI will fund pilot studies using innovative molecular technologies, beyond standard DNA sequencing, to identify genes or variants causing rare genetic disorders, with applications opening in 2026.
Funder: National Institutes of Health
Due Dates: October 30, 2026
Funding Amounts: Up to $500,000 per award; total program funding estimated at $7,500,000; approximately 10 awards expected.
Summary: Supports innovative experimental or computational approaches to accelerate rare disease diagnosis through advanced genomics research.
Description
This funding opportunity, issued by the National Institutes of Health (NIH), aims to drive transformative advances in the diagnosis of rare genetic diseases. The initiative seeks to support highly innovative projects that reimagine and develop new tools, molecular technologies, or analytical approaches for identifying causal genes and variants underlying rare disorders. Both experimental and computational strategies are encouraged, with the goal of dramatically improving current diagnostic methods and enabling a paradigm shift in the field of rare disease genomics.
